Rejuvenating at the cellular level? What is the popular ingredient "Urotilin A"? ~ Nutritionist's Column Vol. 139

"No matter how much I sleep, I can't get rid of my fatigue." "I feel heavier than before." "I'm worried about my skin's firmness."

For those who are beginning to notice these signs of aging, there is an ingredient that is currently attracting the attention of researchers around the world.
Its name is " Urotilin A. "

 This ingredient activates mitochondria, the energy source of cells, and enables anti-aging at the cellular level. It is produced in the body through the interaction of foods such as pomegranates, nuts, and raspberries with the intestinal environment.

How is urothyrin A produced?

Urotilin A is a metabolite produced when ellagic acid , a type of polyphenol, is converted by intestinal bacteria.
In other words, rather than being ingested directly from food, it is "produced within the body," and the key to this is the presence of specific necessary bacteria in the intestines.

Foods that are high in ellagic acid include:

・Pomegranate
・Walnuts
·raspberry

Even if you ingest these, urothyroidin A will not be produced unless there are converting bacteria in the intestines.
That's why "eating + nurturing your intestines" is so important. 

Function 1: Promotes mitochondrial "rejuvenation"

The greatest feature of Urotilin A is that it activates mitophagy (the process of regenerating mitochondria) .
By removing mitochondria that have deteriorated due to aging or stress and replacing them with new ones,

・Less fatigue
Easy to recover
- Metabolism is slow

 It contributes to the development of an energy-efficient body. 

Function 2: Supports cell "cleaning" and "repair"

Urotilin A promotes autophagy (self-eating) within cells.
Autophagy is a system in which the body "eats itself and recycles itself," with auto meaning "self" and phagy meaning "to eat ."

This is the "cleaning function of the cell" that breaks down and reuses unnecessary proteins and broken organelles.

At the same time, the sirtuin gene (longevity gene) is also activated.
It repairs DNA damage and suppresses inflammation and the aging process.
They are like "repairmen for cells" that "repair damage to cells and restore them to a healthy state."
It repairs DNA , suppresses inflammation, and acts as a brake on aging.

It has been discovered that urotilin A activates both autophagy and sirtuins.
In other words, it can be expected to have the effect of " rejuvenating from the inside " by cleaning the inside of cells while repairing damaged parts at the same time.

What you need to know to " make your own " Urotilin A

Since urotilin A supplements are not yet common in Japan, a realistic approach is to improve the intestinal environment in daily life and aim to produce it internally. 

▼ Eating habits to improve your intestinal environment
・Increase good bacteria with fermented foods (natto, miso, pickled vegetables, etc.)
- Feed your gut bacteria with dietary fiber (seaweed, mushrooms, oatmeal)
・Stimulate autophagy with a mini-fast ( 16- hour fast)
Maintain intestinal balance by avoiding processed foods and refined sugars

 By continuing these measures, you can develop intestines that can produce urothyroidin A.

Urotilin A is a " hopeful ingredient " that extends healthy lifespan

Urotilin A is currently undergoing clinical trials in Europe and the United States for the purpose of treating muscle weakness and maintaining physical strength in the elderly.
It is attracting attention as a new option for natural anti-aging care for people who are concerned about physical changes due to aging.
However, awareness is still low in Japan, so "making it yourself" is a realistic option.
As a result, attention is being paid to natural approaches using food and intestinal care.

 Urotilin A for a " rejuvenating lifestyle from the cell up "

Urothyrin A is

・Mitochondrial regeneration
・Activation of autophagy
・Function of the sirtuin gene 

It is truly an "anti-aging ingredient for cells" that supports these three repair mechanisms.
Improving your intestinal environment and working towards a body that can " produce its own Urotilin A " is the key to addressing fatigue and aging concerns.

Why not start your Urotilin A lifestyle with pomegranate juice and natto?

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